Não adesão ao tratamento ou abandono deste entre adolescentes e jovens vivendo com HIV/aids: scoping review

Autores

DOI:

https://doi.org/10.5294/aqui.2023.23.2.2

Palavras-chave:

Pacientes desistentes do tratamento, adolescente, adulto jovem, HIV, aids, síndrome de imunodeficiência adquirida

Resumo

Objetivo: identificar e mapear a literatura científica da área acerca dos motivos da não adesão ao tratamento ou do abandono deste entre adolescentes e jovens que vivem com HIV/aids. Materiais e método: revisão de escopo com uso da estratégia Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews (PRISMA-ScR) para a apresentação de dados referentes aos motivos da não adesão ao tratamento ou do abandono deste entre adolescentes e jovens que vivem com HIV/aids. Para a busca dos artigos, utilizaram-se de sete fontes de informação: Medline via PubMed, Web of Science, Lilacs, Cinahl, BDEnf, Scopus e Embase, sem recorte temporal, com a estratégia de busca “patient dropouts” OR “abandonment” OR “lack of adherence to medication” AND “adolescent” OR “young adult” AND “Acquired Immunodeficiency Syndrome” OR “HIV” AND “antiretroviral therapy highly active” OR “medication adherence”. Resultados: foram incluídos oito artigos no estudo que contemplavam os motivos da não adesão ao tratamento ou do abandono deste, os quais estavam relacionados ao acesso ao serviço de saúde, às condições sociodemográficas, estruturais, psicossociais e comportamentais, e aos fatores associados à doença ou à medicação. Conclusões: os achados deste estudo evidenciaram o quanto os adolescentes e os jovens são vulneráveis às questões inerentes ao tratamento do HIV/aids e que vários motivos podem influenciar a não adesão a este ou seu abandono.

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Referências

Joint United Nations Program HIV/Aids. Informative Summary. Global HIV statistics. [Internet]. 2020. Available from: https://unaids.org.br/wp-content/uploads/2020/11/2020_11_19_UNAIDS_FactSheet_PORT_Revisada.pdf

World Health Organization. Adolescent Heath [Internet]. 2017. Available from: https://www.who.int/health-topics/adolescent-health/ - tab=tab_1

Brasil. Ministério da Saúde. Secretaria de Vigilância em Saúde. Departamento de DST, aids e hepatites virais. Boletim Epidemiológico de HIV/aids [Internet]. 2021. Disponível em: http://www.aids.gov.br/pt-br/pub/2021/boletim-epidemiologico-hivaids-2021

Dine RD, Bamodu OA, Ntaganira J. Youth health risk behavior: Effects of early sexual debut on HIV incidence among Rwandan youth. J Pub Health. 2021;1-11. DOI: https://doi.org/10.1007/s10389-021-01617-8

Van Wyk BE, Davids LC. Challenges to HIV treatment adherence amongst adolescents in a low socio-economic setting in Cape Town. South Afr J HIV Med. 2019;20(1):1002. DOI: https://doi.org/10.4102/sajhivmed.v20i1.1002

Ravanholi GM, Catoia EA, Andrade RLDP, Lopes LM, Brunello MEF, Bollela VR et al. People living with HIV/AIDS in prison: Regular use of antiretroviral therapy. Acta Paul Enferm. 2019;32:521-9. DOI: https://doi.org/10.1590/1982-0194201900073

Rodrigues M, Maksud I. Abandono de tratamento: itinerários terapêuticos de pacientes com HIV/Aids. Saúde Debate. 2017;41(113):526-38. DOI: https://doi.org/10.1590/0103-1104201711314

Nuñez S, Blugerman G, Rollon MJ, Pérez H. Discontinuation and factors associated with abandonment of the first antiretroviral therapy (ART) in HIV-1-Positive Adults. International J Infect Dis. 2018;73(supl):242. DOI: https://doi.org/10.1016/j.ijid.2018.04.3966

Peters MDJ, Godfrey C, McInerney P, Munn Z, Tricco AC, Khalil H. Chapter 11: Scoping reviews (2020 version). In: Aromataris E, Munn Z (Editors). JBI Manual for Evidence Synthesis, JBI Manual for Evidence Synthesis, JBI; 2020. DOI: https://doi.org/10.46658/JBIMES-20-12

Munn Z, Peters MDJ, Stern C, Tufanaru C, McArthur A, Aromataris E. Systematic review or scoping review? Guidance for authors when choosing between a systematic or scoping review approach. BMC Med Res Methodol. 2018; 18:143. DOI: https://doi.org/10.1186/s12874-018-0611-x

Tricco AC, Lillie E, Zarin W, O’Brien KK, Colquhoun H, Levac D et al. PRISMA extension for scoping reviews (PRISMA-ScR): Checklist and explanation. Ann Intern Med. 2018;169(7):467-73. DOI: https://doi.org/10.7326/M18-0850

Ndiaye M, Nyasulu P, Nguyen H, Lowenthal ED, Gross R, Mills EJ, Nachega JB. Risk factors for suboptimal antiretroviral therapy adherence in HIV-infected adolescents in Gaborone, Botswana: A pilot cross-sectional study. Patient Prefer Adherence. 2013;7:891-5. DOI: https://doi.org/10.2147/PPA.S47628

Hawkins A, Evangeli M, Sturgeon K, Le Prevost M, Judd A, AALPHI Steering Committee. Episodic medication adherence in adolescents and young adults with perinatally acquired HIV: A within-participants approach. AIDS Care. 2016;28 Suppl 1(sup1):68-75. DOI: https://doi.org/10.1080/09540121.2016.1146210

Kim MH, Mazenga AC, Yu X, Ahmed S, Paul ME, Kazembe PN et al. High self-reported non-adherence to antiretroviral therapy amongst adolescents living with HIV in Malawi: Barriers and associated factors. J Int AIDS Soc. 2017;20(1):21437. DOI: https://doi.org/10.7448/IAS.20.1.21437

Gaitho D, Kumar M, Wamalwa D, Wambua GN, Nduati R. Understanding mental health difficulties and associated psychosocial outcomes in adolescents in the HIV clinic at Kenyatta National Hospital, Kenya. Ann Gen Psychiatry. 2018;17:29. DOI: https://doi.org/10.1186/s12991-018-0200-8

Anokye-Kumatia AB, Enimil A, Afriyie DK, Tetteh R, Mensah NK, Amo AA et al. Highly active antiretroviral therapy adherence among perinatally infected HIV adolescents at a teaching hospital in Ghana. AIDS Care. 2018;30(9):1144-6. DOI: https://doi.org/10.1080/09540121.2018.1494263

Lantche MW, Fokam J, Cheudjui AJN, Tchatchueng JBM, Noumsi TSJ, Ateba FN et al. Factors associated with non-adherence to antiretroviral therapy among HIV-infected adolescents aged 15-19 years: A snapshot from the Mother and Child Center in Yaounde, Cameroon. Pan Afr Med J. 2021; 39:154. DOI: https://doi.org/10.11604/pamj.2021.39.154.27623

Pinho ECC, Cunha TAN, Lemos M, Ferreira GRON, Lourenção LG, Pinheiro HHC et al. Acesso e acessibilidade na atenção primária à saúde no Brasil. Enferm Foco. 2020;11(2):168-75. DOI: https://doi.org/10.21675/2357-707X.2020.v11.n2.3449

Masiano SP, Martin EG, Bono RS, Dahman B, Sabik LM, Belgrave FZ et al. Suboptimal geographic accessibility to comprehensive HIV care in the US: Regional and urban-rural differences. J Int AIDS Soc. 2019;22(5):e25286. DOI: https://doi.org/10.1002/jia2.25286

Zhou X, Yuan L, Wu C, Yu Z, Wang L. Measuring spatiotemporal accessibility for pediatric clinical services with multimodal transport modes: An exploratory analysis in Nanjing, China. Int J Health Geogr. 2020;9(10):585. DOI: https://doi.org/10.21203/rs.3.rs-34168/v1

Kang JY, Farkhad BF, Chan MS, Michels A, Albarracin D, Wang S. Spatial accessibility to HIV testing, treatment, and prevention services in Illinois and Chicago, USA. PLoS One. 2022;17(7):e0270404. DOI: https://doi.org/10.1371/journal.pone.0270404

Carvalho ACT, Silva DMR, Brandão NW, Pereira EBF, Menezes MLN, Aquino JM. Percepción de adolescentes escolares masculinos en relación al cuidado de su salud. Enferm Actual Costa Rica. 2019;(37):80-94. DOI: https://doi.org/10.15517/revenf.v0i37.36030

Torres TS, Cox J, Marins LM, Bezerra DR, Veloso VG, Grinsztejn B, Luz PM. A call to improve understanding of Undetectable equals Untransmittable (U = U) in Brazil: A web-based survey. J Int AIDS Soc. 2020;23(11):e25630. DOI: https://doi.org/10.1002/jia2.25630

Coelho LE, Torres TS, Veloso VG, Grinsztejn B, Jalil EM, Wilson EC et al. The prevalence of HIV among men who have sex with men (MSM) and young msm in Latin America and the Caribbean: A systematic review. AIDS Behav. 2021;25(10):3223-37. DOI: https://doi.org/10.1007/s10461-021-03180-5

Nowak RG, Mitchell A, Crowell TA, Liu H, Ketende S, Ramadhani HO et al. Individual and sexual network predictors of HIV incidence among men who have sex with men in Nigeria. J Acquir Immune Defic Syndr. 2019;80(4):444-53. DOI: https://doi.org/10.1097/QAI.0000000000001934

Biressaw S, Abegaz WE, Abebe M, Taye WA, Belay M. Adherence to Antiretroviral Therapy and associated factors among HIV infected children in Ethiopia: unannounced home-based pill count versus caregivers’ report. BMC Pediatr. 2013;13:132. DOI: https://doi.org/10.1186/1471-2431-13-132

Dimenstein M, Simoni ACR, Macedo JP, Nogueira N, Barbosa BCNS, Silva BÍBM. Equidade e acesso aos cuidados em saúde mental em três estados nordestinos. Ciênc Saúde Coletiva. 2021; 26(5):1727-38. DOI: https://doi.org/10.1590/1413-81232021265.04912021

Dybul M, Attoye T, Baptiste S, Cherutich P, Dabis F, Deeks SG et al. The case for an HIV cure and how to get there. Lancet HIV. 2021;8(1):e51-8. DOI: https://doi.org/10.1016/S2352-3018(20)30232-0

Kim J, Lee E, Park BJ, Bang JH, Lee JY. Adherence to antiretroviral therapy and factors affecting low medication adherence among incident HIV-infected individuals during 2009-2016: A nationwide study. Sci Rep. 2018;8(1):3133. DOI: https://doi.org/10.1038/s41598-018-21081-x

Hokama NK, Bonequini JP, Hokama POM. Sigilo, anonimato e confidencialidade de doadores de sangue com HIV. Rev Bioét. 2021;29:287-94. DOI: https://doi.org/10.1590/1983-80422021292466

Sukartini T, Nursalam N, Arifin H. The determinants of willingness to care for people living with HIV-AIDS: A cross-sectional study in Indonesia. Health Soc Care Community. 2021;29(3):809-17. DOI: https://doi.org/10.1111/hsc.13318

Ibrahim K, Herliani YK, Rahayuwati L, Khadijah S, Sutini T. Healthcare needs of people living with human immunodeficiency virus: A qualitative descriptive study. Nurs Open. 2022;9(1):349-57. DOI: https://doi.org/10.1002/nop2.1071

Lall P, Lim SH, Khairuddin N, Kamarulzaman A. Review: An urgent need for research on factors impacting adherence to and retention in care among HIV-positive youth and adolescents from key populations. J Int AIDS Soc. 2015;18(2 suppl 1):19393. DOI: https://doi.org/10.7448/IAS.18.2.19393

Brandelli AC, Moura JBF, Silva JM, Beloqui JA, Espindola Y, Araujo CF et al. Key and general population HIV-related stigma and discrimination in HIV-specific health care settings: Results from the Stigma Index Brazil. AIDS Care. 2022;34(1):16-20. DOI: https://doi.org/10.1080/09540121.2021.1876836

Kacanek D, Malee K, Mellins CA, Tassiopoulos K, Smith R, Grant M et al. Exposure to violence and virologic and immunological outcomes among youth with perinatal HIV in the pediatric HIV/AIDS cohort study. J Adolesc Health. 2016;59(1):30-7. DOI: https://doi.org/10.1016/j.jadohealth.2016.03.004

Monteiro WF, Travassos MCP, Ferreira DS, Gonçalves MJF, Honorato EJS, Teixeira E et al. Representações sociais do HIV/AIDS para profissionais de saúde em contexto amazônico: diferentes escolaridades e seus consensos. Ciênc Cuid Saúde. 2021;20:e53394. DOI: https://doi.org/10.4025/ciencuidsaude.v20i0.53394

Lightfoot M, Milburn N, Loeb Stanga L. Addressing Health Disparities in HIV: Introduction to the Special Issue. J Acquir Immune Defic Syndr. 2021;88(S1):S1-5. DOI: https://doi.org/10.1097/QAI.0000000000002804

Elbadawi A, Mirghani H. Depression among HIV/AIDS Sudanese patients: A cross-sectional analytic study. Pan Afr Med J. 2017;26(43):1-8. DOI: https://doi.org/10.11604/pamj.2017.26.43.10919

Freitas JP, Sousa LR, Cruz MC, Caldeira NM, Gir E. Antiretroviral therapy: Compliance level and the perception of HIV/Aids patients. Acta Paul Enferm. 2018;31(3):327-33. DOI: https://doi.org/10.1590/1982-0194201800046

Frigati LJ, Brown K, Cotton MF, Myer L, Zar HJ. Hospitalization in South African adolescents with perinatally acquired HIV on antiretroviral therapy. Pediatr Infect Dis J. 2020;39(11):1035-9. DOI: https://doi.org/10.1097/INF.0000000000002826

Rein SM, Lampe FC, Chaloner C, Stafford A, Rodger AJ, Johnson MA et al. Causes of hospitalisation among a cohort of people with HIV from a London Centre followed from 2011 to 2018. BMC Infect Dis. 2021;21(1):395. DOI: https://doi.org/10.1186/s12879-021-06082-y

Garvie PA. Disclosure of HIV status to youth with perinatally-acquired HIV: The dilemma, risks, and responsibilities. Journal of Adolescent Health. 2021;68(2021):639e641. DOI: https://doi.org/10.1016/j.jadohealth.2021.01.007

Masese RV, Ramos JV, Rugalabamu L, Luhanga S, Shayo AM, Stewart KA et al. Challenges and facilitators of transition from adolescent to adult HIV care among young adults living with HIV in Moshi, Tanzania. J Int AIDS Soc. 2019;22(10):e25406. DOI: https://doi.org/10.1002/jia2.25406

Madan-Patel G, Mazumdar V. Clinical profile and disease progression of HIV in adolescents and young adults in Vadodara, India. Indian J Sex Transm Dis AIDS. 2021;42(1):24-30. DOI: https://doi.org/10.4103/ijstd.IJSTD_6_20

Ammon N, Mason S, Corkery JM. Factors impacting antiretroviral therapy adherence among human immunodeficiency virus-positive adolescents in Sub-Saharan Africa: A systematic review. Public Health.2018;157:20-31. DOI: https://doi.org/10.1016/j.puhe.2017.12.010

Kalichman SC, Katner H, Hill M, Ewing W, Kalichman M. O Perceived sensitivity to medicines and the experience of side-effects: Understanding intentional medication nonadherence among people living with HIV. Psychol Health Med. 2021;1-12. DOI: https://doi.org/10.1080/13548506.2021.1960391

Loch AP, Nemes MIB, Santos MA, Alves AM, Melchior R, Basso CR et al. Avaliação dos serviços ambulatoriais de assistência a pessoas vivendo com HIV no Sistema Único de Saúde: estudo comparativo 2007/2010. Cad Saúde Pública. 2018;34(2):e00047217. DOI: https://doi.org/10.1590/0102-311x00047217

Oh KS, Han E. A comparison of medication adherence and viral suppression in antiretroviral treatment-naïve patients with HIV/AIDS depending on the drug formulary. PLoS One. 2021;16(1):e0245185. DOI: https://doi.org/10.1371/journal.pone.0245185

Miranda MMF, Oliveira DR, Quirino GS, Oliveira CJ, Pereira MLD, Cavalcante EGR. Adherence to antiretroviral therapy by adults living with HIV/aids: A cross-sectional study. Rev Bras Enferm. 2022;75(2):e20210019. DOI: https://doi.org/10.1590/0034-7167-2021-0019

Jerene D, Tiberg I, Hallström I. How can clinical outcomes among adolescents living with HIV in Ethiopia be improved? Healthcare Professionals’ Perspectives. Compr Child Adolesc Nurs. 2021;1-10. DOI: https://doi.org/10.1080/24694193.2021.1914774

Mammbona AA, Mavhandu-Mudzusi AH. Enrolled nurses’ experiences of caring for patients living with HIV in a South African rural hospital. Int Nurs Rev. 2019;66(1):139-46. DOI: https://doi.org/10.1111/inr.12480

Publicado

2023-04-10

Como Citar

Piran, C. M. G., Magalhães, L. G., Shibukawa, B. M. C., Rissi, G. P., Merino, M. de F. G. L., & Furtado, M. D. (2023). Não adesão ao tratamento ou abandono deste entre adolescentes e jovens vivendo com HIV/aids: scoping review. Aquichan, 23(2), e2322. https://doi.org/10.5294/aqui.2023.23.2.2

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